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| Página Principal ::: Recista ATLA Volumenes 26-25 | |||||||||||
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Volume
26 Volume
26, Number 1 CONTENTS EDITORIAL The production of
genetically modified animals and humans: an inescapable moral challenge
to scientists and laypeople alike ECVAM NEWS & VIEWS LETTER FROM CAAT LETTER FROM THE NCA ARTICLES ECVAM Workshop Report
The use of transgenic
animals in the European Union. A quantitative structure-toxicokinetic
relationship model for highly metabolised chemicals. The neutral red uptake
assay: comments on the results of the Instituto Superiore di Sanitá
in the EC/HO validation study. COMMENT Challenging the regulatory
authorities to justify their requirements. CONFERENCE DIARY BOOK REVIEWS Laboratory animal
management: dogs / Information resources for adjuvants and antibody production:
comparisons and alternative technologies 1990-1997 / Vivisection unveiled
/ Laboratory animal management: rodents Volume
26, Supplement 1 MEIC EVALUATION OF ACUTE SYSTEMIC TOXICITY Part III In Vitro Results from
16 Additional Methods Used to Test the First 30 Reference Chemicals and
a Comparative Cytotoxicity Analysis In
Vitro Results from 67 Toxicity Assays Used to Test Reference Chemicals
31-50 and a Comparative Cytotoxicity Analysis CONTENTS EDITORIAL Reducing the use of
laboratory animals: time for strategic actions and the setting of realistic
targets LETTER FROM CAAT LETTER FROM THE NCA ARTICLES
The coumarin 7-hydrozylation
microassay in living hepatic cells in culture. In vitro studies on
the metabolism and toxicity of aflatoxin B1 in primary cultures of black
catfish (Ictalurus melas) hepatocytes.
Anti-ageing efficacy
screening. CONFERENCE DIARY BOOK REVIEWS The pharmaceutical
R&D compendium / Ersatz- und ergänzungsmethoden zu tierversuchen
/ Laboratory animal endocrinology / Target organ pathology: a basic text
Volume
26, Number 3 CONTENTS EDITORIAL Transgenic animals:
more than "commercial" opportunities LETTER FROM CAAT LETTER FROM THE NCA ARTICLES ECVAM Workshop Report
A comparison of the
acute and chronic effects of antidepressants in cultured C6 and 1321N1
cells. Direct determination
of glutathione S-transferase and glucose-6-phosphate dehydrogenase activities
in cells cultured in microtitre plates as biomarkers for oxidative stress.
Toxicity and cell
density monitoring in monolayer and three-dimensional cultures with the
XTT assay. Magnetic resonance
imaging of the common marmoset head. CONFERENCE DIARY BOOK REVIEWS Animal welfare aspects
in the quality control of immunobiologicals: a critical evaluation of
the animal tests in pharmacopoeial monographs / Guide for the care and
use of laboratory animals / Biological aspects of disease: contributions
from animal models / Volunteers in research and testing Volume
26, Number 4 CONTENTS EDITORIAL The FRAME Reduction
Initiative ECVAM NEWS & VIEWS 3RD WORLD CONGRESS LETTER FROM CAAT LETTER FROM THE NCA ARTICLES
Effects of inducers
of drug metabolism on cytosolic glutathione S-transferase activity in
rat hepatoma-derived Fa32 cells. Monitoring method
as a basis for need-based control of varroa mites (Varroa jacobsoni) infesting
honey bee (Apis mellifera) colonies. The use of biomarkers
as alternatives to current animal tests on food chemicals. In vitro models for
studying renal stone formation: a clear alternative. The use of simultaneous
fluorescence and differential phase confocal microscopy to study Alamar
BLueTM reduction in an epithelial cell line. A call for a European
prohibition of monoclonal antibody production by the ascites procedure
in laboratory animals. Influence of slice
thickness and culture conditions on the metabolism of 7-ethoxycoumarin
in precision-cut rat liver slices. Comments on Appendix
C of the National Institutes of Health response to the petition of the
American Anti-Vivisection Society to prohibit the use of animals in the
production of monoclonal antibodies. CONFERENCE DIARY BOOK REVIEWS Animal rights and
wrongs: a biblical perspective / Target 2000: reducing animal experiments
by 50% Volume
26, Number 5 CONTENTS EDITORIAL Biopharmaceuticals
-- from animals or plants? 3RD WORLD CONGRESS LETTER FROM CAAT ARTICLES ECVAM Workshop Report
Progress in toxicological
testing: reduction and refinement issues. Comparative evaluation
of in vitro and in vivo assays for the detection of avian infectious bronchitis
virus as a contaminant for live poultry vaccines. A germination bioassay
as a toxicological screening system for studying the effects of potential
prodrugs of naproxen. Alternative approaches
and tests in ecotoxicology: a review of the present position and the prospects
for change, taking into account ECVAM's duties, topic selection and test
criteria. A study on UV filter
chemicals from Annex VII of European Union Directive 76/768/EEC, in the
in vitro 3T3 NRU phototoxicity test. An evaluation of the
proposed OECD testing strategy for skin corrosion. BOOK REVIEWS Animal models of human
psychology: critique of science, ethics & policy Volume
26, Number 6 CONTENTS EDITORIAL Screening for endocrine
disruptors -- time for more science and less politics LETTER FROM CAAT ARTICLES ECVAM Workshop Report
The availability of
human tissue for biomedical research. The development and
characterisation of a structure-activity relationship model of the Draize
eye irritation test. Report on the COLIPA
workshop on mechanisms of eye irritation. In vitro models of
the blood-brain barrier. BOOK REVIEWS Conflict or concord?:
animal welfare and the World Trade Organization / Animal rights: political
and social change in Britain since 1800 / Genetic engineering: dreams
& nightmares AUTHOR INDEX SUBJECT INDEX CONTENTS EDITORIAL Chimpanzees should
not be used for research on BSE CAAT LETTER ARTICLES ECVAM Workshop Report
Progress toward the
validation of alternative tests. Preselection of potential
cancerostatics by automatic analysis of suspended and adherent cells incubated
in mircoplates. Toxicity of 20 chemicals
from the MEIC programme determined by growth inhibition of L-929 fibroblast-like
cells. COMMENT Frame and the pharmaceutical
industry A bibliometric evaluation
of the performance of ATLA CONFERENCE DIARY BOOK REVIEWS Animal clinical chemistry:
a primer for toxicologists / Alternative methods in toxicology series
volume 10, in vitro skin toxicology: irritation, phototoxicity, sensitization
/ Animal rights and wrongs CONTENTS EDITORIAL The replacement of animal tests:the end of the road or the beginning of harvest-time? NEWS & VIEWS ECVAM MEWS & VIEWS ARTICLES Clive Hollands OBE (1929-1996): The compassionate bugler. L.Ward & others ECVAM Workshop Report
Studies on a-hexaxhlorocyclohexane, cytotoxicity, genotoxicity and cytochrome P450 induction in primary hepatocytes and hepatoma cell lines from rodents and humans. M. ferro, A.M. Bassi, D. Adamo, F. Mattioli, M. Angiola, L. Fazzuoli, F. Razzetta & A. Martelli Interleukin-1a and interleukin-8 release by human keratinocyte cell culture treated with surfactants. M. Shibata, T. Tsuda, H. Itagaki, S.Kato, T. Kobayashi, H. Ichikawa & Y. Morikawa The lipopeptide, Pam3Cys-Ser (Lys)4: an alternative adjuvant to Freund´s adjuvant for the immunisation of chicken to produce egg yolk antibodies. M.H. Erhard, P. Shmidt, A. Hofmann, J. bergman, P. Mittermeier, P. Kaufmann, K-H.Wiesmuller, W.G. Bessler & U. Losch COMMENT Simolarities and differences between animal species and man, with special reference to rheumatoid arthritis and diabetes mellitus. K. Forslund Defining a "threshold of regulation" : the ultimate alternative for safety assessment? R.D. Combes AROUND THE WORLD Mad cows, chimpanzees
and other so-called evolved primates. The Scientific Committee, Pro Anima CONFERENCE DIARY BOOK REVIEWS Volume
25, Number 3
EDITORIAL Non-animal alternatives
and reduction in laboratory animal use ARTICLES ECVAM Workshop Report
The Fourteenth Congress
on In Vitro Toxicology of the Scandinavian Society for Cell Toxicology
An ultrastructural
evaluation of the SKIN2TM ZK1200 system as an in vitro model of the human
oral mucosa. Cadmium-induced inhibition
of ADH-stimulated ion transport in cultured kidney-derived epithelial
cells (A6). An in vitro system
for evaluation of oxidative stress and the effects of antioxidants. 5'-Nucleotidase activity
and galactolipid accumulation in triethyllead-exposed glial cell cultures.
Mechanisms of tamoxifen's
retinal toxicity, studied in pig pigment epithelial cell cultures. Neurotoxicity of seven
MEIC chemicals evaluated in organotypic cultures of chick embryonic dorsal
root ganglia. Genotoxicity screening
of leachates from solid industrial wastes evaluated with the Allium test.
Cytotoxicity of metal
cations used in dental cast alloys. Cytotoxicity of MEIC
chemicals to rainbow trout R1 cell line and multivariate comparison with
ecotoxicity tests. In vitro tets in pharmacotoxicology:
can we fill the gap between scientific advances and industrial needs?.
Cytotoxic and genotoxic
effects of sodium fluoride on mammalian cells at neutral or acid pH: a
summary of published work. An animal protection
sponsor's view of MEIC. Automated in vitro
dermal absorption (AIVDA): a new in vitro method for investigating transdermal
flux. The prediction of
skin permeability by using physicochemical data. A critical analysis
of the testing of the testing of potentially carcinogenic food contaminants
CONFERENCE DIARY BOOK REVIEWS Environmental enrichment
in captive primates: a survey and review / Cytochromes P450: structure,
function and mechanism / In vitro methods in pharmaceutical research Volume
25, Number 4 CONTENTS EDITORIAL Postponement of the
EU ban on animal tests for cosmetic ingredients CAAT LETTER ARTICLES ECVAM Workshop Report
Evaluation of the
cytotoxic effects of MEIC chemicals 31-50 on primary culture of rat hepatocytes
and hepatic and non-hepatic cell lines. The activities of
peptides "31 43", "44-55" and "56-68" of
A-gliadin on in vitro cultures of CaCo-2 cells. A general measure
of in vitro phototoxicity derived from pairs of dose-response curves and
its use for predicting the in vivo phototoxicity of chemicals. COMMENT Ethical considerations
in drug safety testing. CONFERENCE DIARY BOOK REVIEWS CRC handbook of toxicology
/ Glutathione S-transferases: structure function and clinical implications
/ Computer simulations in biomedicine / Toxicology of chemical respiratory
hypersensitivity / Welfare aspects of transgenic animals CONTENTS EDITORIAL Defined structural
and performance criteria would facilitate the validation and acceptance
of replacement of alternative test procedures CAAT LETTER ARTICLES ECVAM Task Force Report
The validation of
toxicological prediction models. In vitro versus in
vivo propagation of monoclonal antibodies: a test case for the effectiveness
of Swedish ethical review committees. Good Laboratory Practice
and study management for the validation of in vitro toxicity studies.
In vitro cytotoxicity
of texile dyes and extracts of dyed/finished fabrics. The effects of two
new amphetamine-like derivatives on the phagocytic ability of the protozoan,
Tetrahymena pyriformis. Advantages of using
egg yolk antibodies in the life sciences: the results of five studies.
The Animals (Scientific
Procedures) Act 1986 as applied to regulatory toxicity testing. NCA symposium on the
use of human material as an alternative to animal experiments. CONFERENCE DIARY BOOK REVIEWS Toxicology: principles
and applications / Cell growth and apoptosis: a practical approach / Environmental
mutagenesis Volume
25, Number 6 CONTENTS EDITORIAL Reducing animal testing:
tests matter more than what is tested LETTER FROM CAAT ARTICLES ECVAM Workshop Report
Reduction of the new
tetrazolium dye, Alamar BlueTM, in cultured rat hepatocytes and liver
fractions. The bioavailability
of substances administered to chick embryos: the maximum effective route
of administration. Evaluation of a commerical
kit for glutathione estimation in cellualr systems. Abstracts of the main
articles published in ALTEX Volume 14 1997 BOOK REVIEWS Animal consciousness
and animal ethics / Mechanisms and concepts in toxicology / From guinea
pig to computer mouse: alternative methods for a humane education / Principles
of exotoxicology.
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Nacional de Colombia Red de Bioética - Instituto de Biotecnología IBUN - 2002 Ciudad Universitaria - Edificio Manuel Ancízar Teléfono 3165000 Ext. 16962 
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