RED DE BIOETICA
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ATLA
(Alternatives To Laboratory Animals) Volume
12, Number 1 CONTENTS EDITORIAL NEWS & VIEWS
Alternative tests
for teratogenicity. Assessment of the
skin irritancy potential of synthetic detergents (syndets). Effects of subacute
concentrations of acrylamide on the morphology of cultured mouse neuroblastoma
NIE115: a time-lapse cinemicrographic study. U.S. scientists active
in animal welfare CONFERENCE DIARY CONFERENCE REPORTS Symposium on imperatives
in research animal use / New approaches to toxicological assessment Volume
12, Number 2 CONTENTS EDITORIAL NEWS & VIEWS
The LD50 value --
a frequently misapplied concept. Continuous cell lines
derived from human tumours as in vitro models for cancer chemotherapy:
a review. The effect of practolol,
in vitro generated metabolites of practolol and chemical analogues on
the rate of growth of human skin fibroblasts. AROUND THE WORLD Revision of the Animal
Protection Act in West Germany BOOK REVIEWS CONFERENCE DIARY CONFERENCE REPORTS Animal rights / In
vitro toxicology / Priorities in animal welfare / Pain in animals / Animal
experimentation -- improvements and alternatives: replacement, reduction
and refinement / Urbino workshop
Volume
12, Number 3 CONTENTS EDITORIAL NEWS & VIEWS ARTICLES The effects of surfactants
and hypnotonicity on bovine cornea in vitro: comparison between opacity
and thickness. Serum-free cultivation
of human scalp hair follicle keratinocytes: a possible tool for genotoxicity
studies? The rabbit eye irritancy
test -- are there in vitro alternatives? Predictive value of
animal toxicity studies. COMMENT Local committees for
the review of experiments involving animals. Standards in laboratory
animal management / Genetic variability in responses to chemical exposure
/ Report of the UKEMS sub-committee on guidelines for mutagenicity testing,
parts I and II/Readings in mammalian cell culture / Experiments with normal
and transformed cells CONFERENCE REPORTS Biomedical research
involving animals / The predictive value of long-term animal studies /
The in vitro effects of mineral dusts Volume
12, Number 4 CONTENTS EDITORIAL NEWS & VIEWS ARTICLES Effects of antibiotics
and organic solvents on the in vitro cytotoxicity of other chemicals.
A reproducibility
study of the model cavity method for the in vitro toxicity testing of
dental restorative materials. Scientific procedures
on living animals: proposals for reform of the 1876 Cruelty to Animals
Act. COMMENT Seven pillars of folly
-- barriers to reason in laboratory animal welfare. Developing an in vitro
system to replace the Draize rabbit eye irritancy test. LETTERS BOOK REVIEWS CONFERENCE DIARY CONFERENCE REPORTS Detection and relief
of pain in animals SELECTED TITLES INDEX FOR VOLUME 12 Volume
11, Number 1 CONTENTS EDITORIAL NEWS & VIEWS
The bovine lens as
a model for osmotic cataract. Toxicity of detergent-based
commercial products on cells of a mouse line in suspension culture as
a possible screen for the Draize rabbit eye irritation test. To what is the alternative?
CONFERENCE DIARY CONFERENCE REPORTS Alternative approaches
to acute toxicity testing / Alternatives to animals in toxicological assessment
and notification SELECTED TITLES Volume
11, Number 2 CONTENTS EDITORIAL NEWS & VIEWS
Computer simulation
of animal systems in the medical school laboratory. The control of animal
experimentation in the United Kingdom. Rational design of
conformationally flexible drugs The in vitro effects
of mineral dusts LETTERS Pain relief Swedish National Board
for Laboratory Animals (NBLA) Animal in behavioural
research CONFERENCE DIARY CONFERENCE REPORTS Toxicity testing Volume
11, Number 3 CONTENTS EDITORIAL NEWS & VIEWS
In vitro techniques
for the detection of chemicals capable of inducing mitotic chromosome
aneuploidy. Further investigations
on the ileum model as a possible alternative to in vivo eye irritancy
testing. On the application
of cultured neuronal cell lines in neurotoxicology. Effects of fungizone
on the in vitro cytotoxicity of other chemicals. AROUND THE WORLD Safety requirements
for the first use of new drugs and diagnostic agents in mane CONFERENCE REPORTS Biomedical research
involving animals / Toxicity testing and safety assessment / Modelling
and simulation for safety and risk assessment: an alternative to animal
experimentation? SELECTED TITLES Volume
11, Number 4 CONTENTS EDITORIAL NEWS & VIEWS
On the application
of cultured neuronal cell lines in neurotoxicological studies: implications
of acrylamide-induced neurite disintegration. The use of computers
to simulate animal preparations in the teaching of practical pharmacology.
Some applications
of probability in cell culture. The role of the ethical
committee in biomedical research The Johns Hopkins
Center LETTERS Significant reductions
CONFERENCE REPORTS Current practices
for more efficient use of animals in research and testing / Irritation
testing of skin and mucous membranes
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